Data di Pubblicazione:
2012
Citazione:
ICSH recommendations for the measurement of haemoglobin A2 / A.D. Stephens, M. Angastiniotis, E. Baysal, V. Chan, S. Fucharoen, P.C. Giordano, J.D. Hoyer, A. Mosca, B. Wild. - In: INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY. - ISSN 1751-5521. - 34:1(2012 Feb), pp. 1-13.
Abstract:
Although DNA analysis is needed for characterization of the mutations that cause beta-thalassaemia, measurement of the Hb A2 is essential for the routine identification of people who are carriers of beta-thalassaemia. The methods of quantitating Hb A2 are described together with pitfalls in undertaking these laboratory tests with particular emphasis on automated high-performance liquid chromatography and capillary electrophoresis.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Hb A2; HPLC; capillary electrophoresis; recommended methods; haemoglobinopathy; thalassaemia
Elenco autori:
A.D. Stephens, M. Angastiniotis, E. Baysal, V. Chan, S. Fucharoen, P.C. Giordano, J.D. Hoyer, A. Mosca, B. Wild
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