An immunohistochemically positive E-cadherin status is not always predictive for a good prognosis in human breast cancer
Articolo
Data di Pubblicazione:
2010
Citazione:
An immunohistochemically positive E-cadherin status is not always predictive for a good prognosis in human breast cancer / P. Querzoli, D. Coradini, M. Pedriali, P. Boracchi, F. Ambrogi, E. Raimondi, R. La Sorda, R. Lattanzio, R. Rinaldi, M. Lunardi, C. Frasson, F. Modesti, S. Ferretti, M. Piantelli, S. Iacobelli, E. Biganzoli, I. Nenci, S. Alberti. - In: BRITISH JOURNAL OF CANCER. - ISSN 0007-0920. - 103:12(2010 Dec 07), pp. 1835-1839. [10.1038/sj.bjc.6605991]
Abstract:
in primary breast cancers dichotomic classification of E-cadherin expression, according to an arbitrary cutoff, may be inadequate and lead to loss of prognostic significance or contrasting prognostic indications. We aimed to assess the prognostic value of high and low E-cadherin levels in a consecutive case series (204 cases) of unilateral node-negative non-lobular breast cancer patients with a 8-year median follow-up and that did not receive any adjuvant therapy after surgery.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Disease-Free Survival ; Aged, 80 and over ; Humans ; Adult ; Prognosis ; Breast Neoplasms ; Aged ; Middle Aged ; Immunohistochemistry ; Cadherins ; Female
Elenco autori:
P. Querzoli, D. Coradini, M. Pedriali, P. Boracchi, F. Ambrogi, E. Raimondi, R. La Sorda, R. Lattanzio, R. Rinaldi, M. Lunardi, C. Frasson, F. Modesti, S. Ferretti, M. Piantelli, S. Iacobelli, E. Biganzoli, I. Nenci, S. Alberti
Link alla scheda completa: