Data di Pubblicazione:
2003
Citazione:
Ovarian endometriosis: from pathogenesis to surgical treatment / M. Busacca , M. Vignali. - In: CURRENT OPINION IN OBSTETRICS & GYNECOLOGY. - ISSN 1040-872X. - 15:4(2003), pp. 321-326.
Abstract:
PURPOSE OF REVIEW: This review analyzes the literature on ovarian endometrioma,
examining the controversies on pathogenesis, malignant transformation and
surgical therapy. RECENT FINDINGS: Recent literature reflects the necessity of
clearly defining the ethiologic and pathologic factors that determine the origin
of ovarian endometriosis and explain the increase in the condition with the
prospect of developing effective prevention therapy. The possibility that
ovarian endometriomas undergo malignant transformation is widely reported in the
literature. Recent studies underline the importance of detecting histological
differences in endometriosis (hyperplasia and atypia) and several studies of
molecular biology support the theory of genetic alterations interfering with
malignant transformation of ovarian endometriosis. SUMMARY: The surgical
approach must take into account all this information and, when the therapy is
conservative, complete excision of the disease must be laparoscopically
performed without affecting the healthy ovarian tissue.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Endometrioma excision; Endometriosis and cancer; Immunomodulators in endometriosis; Ovarian endometriosis
Elenco autori:
M. Busacca , M. Vignali
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