Data di Pubblicazione:
2010
Citazione:
Rate of severe ovarian damage following surgery for endometriomas / L. Benaglia, E. Somigliana, V. Vighi, G. Ragni, P.P. Vercellini, L. Fedele. - In: HUMAN REPRODUCTION. - ISSN 0268-1161. - 25:3(2010), pp. 678-682. [10.1093/humrep/dep464]
Abstract:
background: There is growing and consistent evidence showing that ovarian reserve is affected following surgical excision of ovarian
endometriomas. Of particular concern is the risk of severe ovarian damage leading to unresponsiveness to ovarian hyperstimulation. In this
study, we aimed to determine the rate of this complication.
methods: Ninety-three women underwent surgery for monolateral endometriomas were recruited. Patients who underwent IVF were
selected and, in all cases, follicular growth was monitored by serial transvaginal ultrasonography. The main outcome measure was the rate of
ovaries remaining silent when stimulated after surgery for endometriomas.
results: Absence of follicular growth was observed in 12 operated ovaries although this event never occurred in the contralateral gonad
(P , 0.001). The frequency (95% confidence interval) of severe ovarian damage following surgery was 13% (7–21%).
conclusions: Severe ovarian damage, occurring in gonads operated on for ovarian endometriomas, is not a rare event.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
endometriosis ; endometrioma ; ovarian failure ; surgery ; IVF
Elenco autori:
L. Benaglia, E. Somigliana, V. Vighi, G. Ragni, P.P. Vercellini, L. Fedele
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