Data di Pubblicazione:
2010
Citazione:
Otitis media and its consequences: beyond the earache / A. Vergison, R. Dagan, A. Arguedas, J. Bonhoeffer, R. Cohen, I. Dhooge, A. Hoberman, J. Liese, P.G. Marchisio, A. Palmu, G.T. Ray, E.A.M. Sanders, E.A.F. Simoes, M. Uhari, J. van Eldere, S.I. Pelton. - In: THE LANCET INFECTIOUS DISEASES. - ISSN 1473-3099. - 10:3(2010), pp. 195-203. [10.1016/S1473-3099(10)70012-8]
Abstract:
An international group of multidisciplinary experts on middle-ear and paediatric infections met to explore where
consensus exists on the management of acute otitis media. After informal discussions among several specialists of
paediatric infectious disease, the group was expanded to include a larger spectrum of professionals with
complementary expertise in middle-ear disease. Acute otitis media is a very common bacterial infection in children
worldwide, leading to excessive antibiotic consumption in children in most countries and to a substantial burden of
deafness and suppurative complications in developing countries. The group attempted to move beyond the existing
controversies surrounding guidelines on acute otitis media, and to propose to clinicians and public health offi cials
their views on the actions needed to be taken to reduce the disease burden caused by acute otitis media and the
microbial antibiotic resistance from the resulting use of antibiotics. Defi nition of acute otitis media and diagnostic
accuracy are crucial steps to identify children who will potentially benefi t from treatment with antibiotics and to
eliminate unnecessary prescribing. Although the group agreed that antibiotics are distributed indiscriminately, even
to children who do not seem to have the disease, no consensus could be reached on whether antibiotics should be
given to all appropriately diagnosed children, refl ecting the wide range of practices and lack of convincing evidence
from observational studies. The major unanimous concern was an urgent need to reduce unnecessary prescribing of
antibiotics to prevent further increases in antibiotic resistance. Prevention of acute otitis media with existing and
future viral and bacterial vaccines seems the most promising approach to aff ect disease burden and consequences,
both in developed and developing countries.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
A. Vergison, R. Dagan, A. Arguedas, J. Bonhoeffer, R. Cohen, I. Dhooge, A. Hoberman, J. Liese, P.G. Marchisio, A. Palmu, G.T. Ray, E.A.M. Sanders, E.A.F. Simoes, M. Uhari, J. van Eldere, S.I. Pelton
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