Biological roles of Acid and neutral sphingomyelinases and their regulation by nitric oxide
Articolo
Data di Pubblicazione:
2010
Citazione:
Biological roles of Acid and neutral sphingomyelinases and their regulation by nitric oxide / C. Perrotta, E.G.I. Clementi. - In: PHYSIOLOGY. - ISSN 1548-9213. - 25:2(2010), pp. 64-71. [10.1152/physiol.00048.2009]
Abstract:
Generation of the pleiotropic sphingolipid mediator ceramide by acid and neutral sphingomyelinases is a key event in many cellular pathophysiological processes including survival, death, proliferation, and differentiation, in which also the short-lived gaseous messenger nitric oxide plays a crucial role. This review describes how the outcome of these key cellular processes is finely tuned by surprising and complex interplays among nitric oxide, ceramide, and their effectors.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
C. Perrotta, E.G.I. Clementi
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