Forgetting RSPO1

This clinical condition, which is extremely rare, is very interesting
for researchers involved in studies regarding sex determination
processes, because the molecular analysis of such patients could
lead to the discovery of genes involved in testis differentiation in
the absence of the master gene SRY. Unfortunately, the article
includes a number of inaccuracies and omissions regarding the state
of the art on clinical features and genetic studies of this condition in
human patients and animal models. Consequently some aspects of it
ought to be revised or clarified.