Data di Pubblicazione:
2002
Citazione:
Biomarkers for endocrine disruptors in three species of Mediterranean large pelagic fish / M.C. Fossi, S. Casini, L. Marsili, G. Neri, G. Mori, S. Ancora, A. Moscatelli, A. Ausili, G. Notarbartolo di Sciara. - In: MARINE ENVIRONMENTAL RESEARCH. - ISSN 0141-1136. - Disco ottico. - 54:3-5(2002), pp. 667-671.
Abstract:
The hypothesis that Mediterranean top predator species, such as large pelagic fish, are potentially at risk due to endocrine disrupting chemicals (EDCs), is investigated. The potential estrogenic effects of PHAHs in three fish species of commercial interest, the top predators bluefin tuna (Thunnus thynnus thynnus), swordfish (Xiphias gladius), and Mediterranean spearfish (Tetrapturus belone), were investigated using vitellogenin (Vtg), zona radiata proteins (Zrp) and mixed function oxidases (EROD, BPMO) as diagnostic tools. High induction of Vtg and Zrp was detected by western blot and ELISA techniques in adult males of X. gladius and T. thynnus thynnus, suggesting that these species are at high toxicological risk in the Mediterranean sea. Comparison of BPMO and EROD activities in the three species indicated, both in male and female, much higher MFO activity in bluefin tuna. This data suggests high exposure of this species to lipophilic xenobiotic contaminants in the Mediterranean environment.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Thunnus thynnus thynnus ; Xiphias gladius ; Tetrapturus belone ; EDCs ; Vtg ; Zrp ; Erod ; BPMO
Elenco autori:
M.C. Fossi, S. Casini, L. Marsili, G. Neri, G. Mori, S. Ancora, A. Moscatelli, A. Ausili, G. Notarbartolo di Sciara
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