Data di Pubblicazione:
2024
Citazione:
Bacteriophage therapy in companion and farm animals / L. Bianchessi, G. De Bernardi, M. Vigorelli, P. Dall'Ara, L. Turin. - In: ANTIBIOTICS. - ISSN 2079-6382. - 13:4(2024 Mar 25), pp. 294.1-294.22. [10.3390/antibiotics13040294]
Abstract:
Bacteriophages, which are viruses with restricted tropism for bacteria, have been employed
for over a century as antimicrobial agents; they have been largely abandoned in Western countries but
are constantly used in Eastern European countries with the advent of antibiotics. In recent decades,
the growing spread of multidrug-resistant bacteria, which pose a serious threat to worldwide public
health, imposed an urgent demand for alternative therapeutic approaches to antibiotics in animal
and human fields. Based on this requirement, numerous studies have been published on developing
and testing bacteriophage-based therapy. Overall, the literature largely supports the potential of
this perspective but also highlights the need for additional research as the current standards are
inadequate to receive approval from regulatory authorities. This review aims to update and critically
revise the current knowledge on the application of bacteriophages to treat bacterial-derived infectious
diseases in animals in order to provide topical perspectives and innovative advances.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
bacteria; bacteriophage; phage; therapy; challenge; alternative antimicrobials; veterinary; antibacterial; multidrug resistant
Elenco autori:
L. Bianchessi, G. De Bernardi, M. Vigorelli, P. Dall'Ara, L. Turin
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