Budesonide and formoterol combination for the treatment of chronic obstructive pulmonary disease
Articolo
Data di Pubblicazione:
2005
Citazione:
Budesonide and formoterol combination for the treatment of chronic obstructive pulmonary disease / S. Centanni, F. Di Marco. - In: EXPERT OPINION ON PHARMACOTHERAPY. - ISSN 1465-6566. - 6:14(2005 Nov), pp. 2525-2534.
Abstract:
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality throughout the world. Current guidelines recommend the addition of inhaled steroids to bronchodilators, which are central to the symptomatic management of COPD in patients with severe disease. Budesonide/formoterol is a combination inhaled steroid and long-acting bronchodilator delivered by a dry-powder inhaler, approved for use in COPD. Two large, randomised, double-blind, 12-month studies found that combination budesonide/formoterol is more effective than either component alone in addressing many important aspects of the disease, such as pulmonary function, symptoms, use of relief medication, health-related quality of life and exacerbation in patients suffering from severe COPD. This review discusses the pharmacological and clinical properties of the drug.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
β-agonists; Budesonide; Chronic obstructive pulmonary disease; Formoterol; Inhaled steroids
Elenco autori:
S. Centanni, F. Di Marco
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