Equating norms between the ALS Cognitive Behavioral Screen (ALS-CBS™) and the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) in non-demented ALS patients
Articolo
Data di Pubblicazione:
2023
Citazione:
Equating norms between the ALS Cognitive Behavioral Screen (ALS-CBS™) and the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) in non-demented ALS patients / E.N. Aiello, F. Solca, L.C. Greco, S. Torre, L. Carelli, C. Morelli, A. Doretti, E. Colombo, S. Messina, D. Pain, A. Radici, A. Lizio, J. Casiraghi, F. Cerri, S. Woolley, J. Murphy, L. Tremolizzo, I. Appollonio, F. Verde, V.A. Sansone, C. Lunetta, V. Silani, N. Ticozzi, B. Poletti. - In: JOURNAL OF NEUROLOGY. - ISSN 0340-5354. - 270:8(2023 Aug), pp. 4090-4095. [10.1007/s00415-023-11749-4]
Abstract:
BackgroundThe present study aimed at deriving equating norms to estimate scores on the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) based on those on the ALS Cognitive Behavioral Screen (ALS-CBS (TM)) in an Italian cohort of non-demented ALS patients.MethodsALS-CBS (TM) and ECAS scores of 293 ALS patients without frontotemporal dementia were retrospectively retrieved. Concurrent validity of the ALS-CBS (TM) towards the ECAS was tested by covarying for demographics, disease duration and severity, presence of C9orf72 hexanucleotide repeat expansion and behavioural features. A linear-smoothing equipercentile equating (LSEE) model was employed to derive ALS-CBS (TM)-to-ECAS cross-walks. Gaps in LSEE-based estimation were managed via a linear regression-based equating approach. Equivalence between empirical and derived ECAS scores was tested via a two-one-sided test (TOST) procedure for the dependent sample.ResultsThe ALS-CBS (TM) predicted the ECAS (beta = 0.75), accounting for the vast majority of its variance (60% out of an R-2 = 0.71). Consistently, a strong, one-to-one linear association between ALS-CBS (TM) and ECAS scores was detected (r = 0.84; R-2 = 0.73). The LSEE was able to estimate conversions for the full range of the ALS-CBS (TM), except for raw scores equal to 1 and 6 - for whom a linear equating-based equation was derived. Empirical ECAS scores were equivalent to those derived with both methods.DiscussionItalian practitioners and researchers have been herewith provided with valid, straightforward cross-walks to estimate the ECAS based on ALS-CBS (TM) scores in non-demented ALS patients. Conversions herewith provided will help avoid cross-sectional/longitudinal inconsistencies in test adoption within research, and possibly clinical, settings.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
ALS Cognitive Behavioral Screen; Amyotrophic lateral sclerosis; Edinburgh Cognitive and Behavioural ALS Screen; Equating; Frontotemporal degeneration
Elenco autori:
E.N. Aiello, F. Solca, L.C. Greco, S. Torre, L. Carelli, C. Morelli, A. Doretti, E. Colombo, S. Messina, D. Pain, A. Radici, A. Lizio, J. Casiraghi, F. Cerri, S. Woolley, J. Murphy, L. Tremolizzo, I. Appollonio, F. Verde, V.A. Sansone, C. Lunetta, V. Silani, N. Ticozzi, B. Poletti
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