Data di Pubblicazione:
2010
Citazione:
Evaluation of microalbuminuria in patients with erectile dysfunction / A. Barassi, R. Pezzilli, A.M. Morselli-Labate, W. Porreca, G. Piediferro, F. Ciociola, G. Colpi, G.V. Melzi d'Eril. - In: JOURNAL OF SEXUAL MEDICINE. - ISSN 1743-6095. - 7:3(2010), pp. 1224-1228. [10.1111/j.1743-6109.2009.01503.x]
Abstract:
Introduction: The recent sophisticated diagnostic procedures aimed at identifying the exact cause of erectile dysfunction (ED) are often complicated in clinical application, invasive, or highly expensive. Microalbuminuria, a test easy to perform and of low cost, is a marker of extensive endothelial dysfunction, and it has been suggested to be linked to ED. Aim: The aim of this study was to investigate the eventual role of microalbuminuria in differentiating patients with arteriogenic and non arteriogenic ED. Methods: The diagnosis of ED was based on the International Index of Erectile Function 5-questionnaire, and patients were classified as arteriogenic (N = 29) and non-arteriogenic (N = 49) in relation to the results of echo-color-doppler examination of cavernosal arteries in basal conditions and after intracavernous injection of 10 μg prostaglandin E1. Main Outcome Measures: The microalbuminuria of 78 males without the most common atheriosclerotic risks and with ED was measured. Results: Microalbuminuria, defined as urinary albumin/creatinine ratio, was not significantly (P > 0.05) different between patients of the two groups. Conclusions: Our data show that in ED patients the cavernosal arteries damage, as assessed by dynamic echo-color-doppler, may be independent on or precede extensive endothelial dysfunction, and that microalbuminuria cannot be predictive of penile arteriogenic etiology.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Cardiovascular risk for erectile dysfunction; Endothelial function; Erectile dysfunction; Microalbuminuria
Elenco autori:
A. Barassi, R. Pezzilli, A.M. Morselli Labate, W. Porreca, G. Piediferro, F. Ciociola, G. Colpi, G.V. Melzi d'Eril
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