Exclusive human milk feeding and prevalence of early adiposity rebound in ELBW infants: a retrospective cohort study
Articolo
Data di Pubblicazione:
2023
Citazione:
Exclusive human milk feeding and prevalence of early adiposity rebound in ELBW infants: a retrospective cohort study / J. Cerasani, A. Consales, S. Gangi, M. Macchi, D. Morniroli, G. Vizzari, V. Tiraferri, A. Petrelli, F. Mosca, M.L. Giannì. - In: EUROPEAN JOURNAL OF PEDIATRICS. - ISSN 0340-6199. - (2023), pp. 1-9. [Epub ahead of print] [10.1007/s00431-023-05374-6]
Abstract:
The purpose of the present study was to evaluate the prevalence of early adiposity rebound (EAR) and factors associated with
its occurrence in a cohort of extremely low birth weight infants (ELBW). We conducted a retrospective longitudinal study
including ELBW infants followed-up for up to 10 years after discharge. EAR was defined as occurring before 5 years of age.
A multivariate binary logistic regression analysis was performed to evaluate maternal and perinatal variables independently
associated with EAR. Out of 212 ELBW infants included in the analysis, 40.6% developed EAR and 21.5% showed it before
4 years of age. Only formula milk feeding at discharge was independently associated with a higher risk of EAR. The mean
BMI of children with EAR was higher than that of children without EAR. Furthermore, the prevalence of overweight and
obesity was higher in the EAR group than in the timely AR group.
Conclusions: ELBW infants in our cohort developed EAR in a relatively high percentage of cases. In this already at-risk
population, EAR may represent a further risk factor for an adverse metabolic outcome. Monitoring preterm infants’ growth
within a long-term follow-up program and promoting and supporting human milk feeding is advisable.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
ELBW infants; Early adiposity rebound; Human milk; Metabolic outcomes
Elenco autori:
J. Cerasani, A. Consales, S. Gangi, M. Macchi, D. Morniroli, G. Vizzari, V. Tiraferri, A. Petrelli, F. Mosca, M.L. Giannì
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