Verbal Learning Impairment in Parkinson's Disease: Role of the Frontostriatal System in Working and Strategic Memory
Articolo
Data di Pubblicazione:
2023
Citazione:
Verbal Learning Impairment in Parkinson's Disease: Role of the Frontostriatal System in Working and Strategic Memory / A. Cocuzza, T. Difonzo, E.N. Aiello, L.P.E. Sbrissa, S. Zago, C. Gendarini, M.A. Sirtori, B. Poletti, N. Ticozzi, G. Franco, A. Di Fonzo, G.P. Comi, M.C. Saetti. - In: NEURODEGENERATIVE DISEASES. - ISSN 1660-2854. - 23:1-2(2023 Dec), pp. 20-24. [10.1159/000534307]
Abstract:
Introduction: Learning is a long-term memory process, influenced by working memory control processes, including recognition of semantic properties of items by which subjects generate a semantic structure of engrams. The aim of the study was to investigate the verbal learning strategies of individuals with Parkinson's disease (PD). Methods: Thirty individuals with idiopathic PD and healthy control (HC) subjects were tested with a multi-trial word list learning, under two conditions: without cue and then with an explicit cue suggesting the categories in the list, respectively. Results: In comparison to HC subjects, individuals with PD recalled fewer words and achieved a reduced number of categorical clusters; the strategical cue did not improve their performance. Conclusion: This suggests, besides a difficulty in identifying the correct learning strategy, a deficit in working memory, which undermines the strategy implementation.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Parkinson’s disease; Strategic memory; Verbal learning;
Elenco autori:
A. Cocuzza, T. Difonzo, E.N. Aiello, L.P.E. Sbrissa, S. Zago, C. Gendarini, M.A. Sirtori, B. Poletti, N. Ticozzi, G. Franco, A. Di Fonzo, G.P. Comi, M.C. Saetti
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