Effect of zirconium nitride physical vapor deposition coating on preosteoblast cell adhesion and proliferation onto titanium screws
Articolo
Data di Pubblicazione:
2014
Citazione:
Effect of zirconium nitride physical vapor deposition coating on preosteoblast cell adhesion and proliferation onto titanium screws / M. Rizzi, G. Gatti, M. Migliario, L. Marchese, V. Rocchetti, F. Reno'. - In: THE JOURNAL OF PROSTHETIC DENTISTRY. - ISSN 0022-3913. - 112:5(2014 Nov), pp. 1103-1110. [10.1016/j.prosdent.2014.04.010]
Abstract:
Statement of problem. Titanium has long been used to produce dental implants. Problems related to its manufacturing, casting, welding, and ceramic application for dental prostheses still limit its use, which highlights the need for technologic improvements. The aim of this in vitro study was to evaluate the biologic performance of titanium dental implants coated with zirconium nitride in a murine preosteoblast cellular model.
Purpose. The purpose of this study was to evaluate the chemical and morphologic characteristics of titanium implants coated with zirconium nitride by means of physical vapor deposition.
Material and methods. Chemical and morphologic characterizations were performed by scanning electron microscopy and energy dispersive x-ray spectroscopy, and the bioactivity of the implants was evaluated by cell-counting experiments.
Results. Scanning electron microscopy and energy dispersive x-ray spectroscopy analysis found that physical vapor deposition was effective in covering titanium surfaces with zirconium nitride. Murine MC-3T3 preosteoblasts were seeded onto titaniumcoated and zirconium nitrideecoated screws to evaluate their adhesion and proliferation. These experiments found a significantly higher number of cells adhering and spreading onto zirconium nitrideecoated surfaces (P<.05) after 24 hours; after 7 days, both titanium and zirconium nitride surfaces were completely covered with MC-3T3 cells.
Conclusions. Analysis of these data indicates that the proposed zirconium nitride coating of titanium implants could make the surface of the titanium more bioactive than uncoated titanium surfaces.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
M. Rizzi, G. Gatti, M. Migliario, L. Marchese, V. Rocchetti, F. Reno'
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