Validation and Verification of High-Fidelity Simulations of Thoracic Stent-Graft Implantation
Articolo
Data di Pubblicazione:
2022
Citazione:
Validation and Verification of High-Fidelity Simulations of Thoracic Stent-Graft Implantation / A. Ramella, F. Migliavacca, J.F. Rodriguez Matas, F. Heim, F. Dedola, S. Marconi, M. Conti, S. Allievi, T.J. Mandigers, D. Bissacco, M. Domanin, S. Trimarchi, G. Luraghi. - In: ANNALS OF BIOMEDICAL ENGINEERING. - ISSN 0090-6964. - 50:12(2022 Dec), pp. 1941-1953. [10.1007/s10439-022-03014-y]
Abstract:
Thoracic Endovascular Aortic Repair (TEVAR) is the preferred treatment option for thoracic aortic pathologies and consists of inserting a self-expandable stent-graft into the pathological region to restore the lumen. Computational models play a significant role in procedural planning and must be reliable. For this reason, in this work, high-fidelity Finite Element (FE) simulations are developed to model thoracic stent-grafts. Experimental crimp/release tests are performed to calibrate stent-grafts material parameters. Stent pre-stress is included in the stent-graft model. A new methodology for replicating device insertion and deployment with explicit FE simulations is proposed. To validate this simulation, the stent-graft is experimentally released into a 3D rigid aortic phantom with physiological anatomy and inspected in a computed tomography (CT) scan at different time points during deployment with an ad-hoc set-up. A verification analysis of the adopted modeling features compared to the literature is performed. With the proposed methodology the error with respect to the CT is on average 0.92 +/- 0.64%, while it is higher when literature models are adopted (on average 4.77 +/- 1.83%). The presented FE tool is versatile and customizable for different commercial devices and applicable to patient-specific analyses.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Endograft; Finite element method; Numerical model; TEVAR;
Elenco autori:
A. Ramella, F. Migliavacca, J.F. Rodriguez Matas, F. Heim, F. Dedola, S. Marconi, M. Conti, S. Allievi, T.J. Mandigers, D. Bissacco, M. Domanin, S. Trimarchi, G. Luraghi
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