Highly stereoselective metal-free catalytic reduction of imines: an easy entry to enantiomerically pure amines and natural and unnatural -amino esters.
Articolo
Data di Pubblicazione:
2009
Citazione:
Highly stereoselective metal-free catalytic reduction of imines: an easy entry to enantiomerically pure amines and natural and unnatural -amino esters / S. Guizzetti, M. Benaglia, S. Rossi. - In: ORGANIC LETTERS. - ISSN 1523-7060. - 11:13(2009), pp. 2928-2931.
Abstract:
A highly efficient catalytic stereoselective ketlmlne reduction is described. The combination of an Inexpensive chiral organocatalyst, easily prepared In a single step, and of a very cheap removable chiral auxiliary allowed us to obtain enantlomerlcally pure amino compounds. The methodology allowed synthesis of chiral secondary and primary amines and natural and unnatural amino esters In high yields often with total control of the absolute stereochemistry.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
S. Guizzetti, M. Benaglia, S. Rossi
Link alla scheda completa: