Enantioselective catalytic addition of nitroesters to N-carboalkyloxy imines : a route to quaternary stereocenters
Articolo
Data di Pubblicazione:
2009
Citazione:
Enantioselective catalytic addition of nitroesters to N-carboalkyloxy imines : a route to quaternary stereocenters / A. Puglisi, L. Raimondi, M. Benaglia, M. Bonsignore, S. Rossi. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 50:30(2009), pp. 4340-4342.
Abstract:
A readily available, low cost bifunctional organic catalyst promoted the addition of nitroesters to imines; in the reaction between 2-nitropropionates and N-Boc protected aldehyde-imines the product bearing a new quaternary stereocenter was obtained in up to 81% ee. The positively charged catalyst was postulated to control the attack of the enolic form of nitroester to imine through a hydrogen bonding network
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Bifuctional catalyst; Catalysis; Nitroesters; Quaternary stereocenter; Synthetic methods
Elenco autori:
A. Puglisi, L. Raimondi, M. Benaglia, M. Bonsignore, S. Rossi
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