Comparison of brain connectomes using geodesic distance on manifold: A twins study
Contributo in Atti di convegno
Data di Pubblicazione:
2019
Citazione:
Comparison of brain connectomes using geodesic distance on manifold: A twins study / A. Yamin, M. Dayan, L. Squarcina, P. Brambilla, V. Murino, V. Diwadkar, D. Sona (PROCEEDINGS INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING). - In: ISBI 2019[s.l] : Institute of Electrical and Electronics Engineers (IEEE), 2019. - ISBN 9781538636411. - pp. 1797-1800 (( Intervento presentato al 16. convegno International Symposium on Biomedical Imaging : April 8-11 tenutosi a Venezia nel 2019 [10.1109/ISBI.2019.8759407].
Abstract:
fMRI is a unique non-invasive approach for understanding the functional organization of the human brain, and task based fMRI promotes identification of functionally relevant brain regions associated with a given task. Here, we use fMRI (using the Poffenberger Paradigm) data collected in mono- and dizygotic twin pairs to propose a novel approach for assessing similarity in functional networks. In particular, we compared network similarity between pairs of twins in task-relevant and task-orthogonal networks. The proposed method measures the similarity between functional networks using a geodesic distance between graph Laplacian. With method we show that networks are more similar in monozygotic twins compared to dizygotic twins. Furthermore, the similarity in monozygotic twins is higher for task-relevant, than task-orthogonal networks.
Tipologia IRIS:
03 - Contributo in volume
Keywords:
Connectomes; task-based fMRI; graph Laplacian; geodesic distance; twins
Elenco autori:
A. Yamin, M. Dayan, L. Squarcina, P. Brambilla, V. Murino, V. Diwadkar, D. Sona
Link alla scheda completa:
Titolo del libro:
ISBI 2019