Hydrogen bond-mediated organocatalytic enantioselective reduction of nitroalkenes in deep eutectic solvents
Articolo
Data di Pubblicazione:
2023
Citazione:
Hydrogen bond-mediated organocatalytic enantioselective reduction of nitroalkenes in deep eutectic solvents / C. Faverio, M.F. Boselli, T. Ruggiero, L. Raimondi, M. Benaglia. - In: TETRAHEDRON CHEM. - ISSN 2666-951X. - 6:(2023 Jun), pp. 1-4. [10.1016/j.tchem.2023.100038]
Abstract:
The catalytic enantioselective reduction of β,β-disubstituted nitroalkenes was performed in deep eutectic solvents, avoiding the use of volatile organic compounds (VOCs) as reaction medium. The desired enantioenriched nitroalkanes were obtained in high yields and high enantiomeric excesses, up to 90%, by a metal-free, hydrogen bond-mediated catalytic methodology, with a convenient experimental protocol that could be successfully applied to a gram-scale reaction.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Deep eutectic solvents; Organocatalysis; Enantioselective reduction; Chiral nitro alkanes; Hydrogen bond-mediated reactions;
Elenco autori:
C. Faverio, M.F. Boselli, T. Ruggiero, L. Raimondi, M. Benaglia
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