Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries
Articolo
Data di Pubblicazione:
2023
Citazione:
Comparison of intraperitoneal and incisional lidocaine or ropivacaine irrigation for postoperative analgesia in dogs undergoing major abdominal surgeries / F.A. Brioschi, G. Ravasio, F. Ferrari, M. Amari, F. Di Cesare, M. Valentini Visentin, V. Rabbogliatti. - In: PLOS ONE. - ISSN 1932-6203. - 18:4(2023 Apr 13), pp. e0284379.1-e0284379.14. [10.1371/journal.pone.0284379]
Abstract:
This study compared the postoperative analgesic efficacy of intraperitoneal and incisional
lidocaine versus ropivacaine in dogs undergoing major abdominal surgeries. Dogs randomly
received intraperitoneal lidocaine irrigation (4 mg kg-1, diluted to 5 ml kg-1, L group), ropiva-
caine (4 mg kg-1, diluted to 5 ml kg-1, R group) or 0.9% saline (5 ml kg-1, C group). Prior to
skin closure, dogs received incisional lidocaine 2 mg kg-1 (group L), incisional ropivacaine 2
mg kg-1 (group R) or incisional saline 0.2 ml kg-1 (group C). Pain was assessed at different
time points up to 24 hours after extubation, using the Short Form-Glasgow Composite Mea-
sure Pain Scale and VAS Scale. In group C, postoperative pain scores were significantly
higher than in groups L and R from T0.5 to T6 (p < 0.05). In R group, postoperative pain
scores were significantly lower than in groups L and C from T12 to T24 (p < 0.05). Rescue
analgesia was administered to 5/11 dogs in L group, 1/10 dogs in R group and 8/10 dogs in
C group. Groups L and R experienced a significantly lower postoperative pain during the
first 6 hours after extubation, compared with group C. Ropivacaine provided lower postoper-
ative pain scores than lidocaine and saline up to 24 hours after extubation. According to the
obtained results, ropivacaine seemed to provide better and longer lasting postoperative
analgesia compared with lidocaine. Therefore, intraperitoneal and incisional administration
of ropivacaine in dogs undergoing major abdominal surgeries is recommended.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
F.A. Brioschi, G. Ravasio, F. Ferrari, M. Amari, F. Di Cesare, M. Valentini Visentin, V. Rabbogliatti
Link alla scheda completa: