Phosphine‐Catalyzed [3+2] Cycloaddition of Aza‐Aurones and Allenoates: Enantioselective Synthesis of 2‐Spirocyclopentyl‐Indolin‐3‐Ones
Articolo
Data di Pubblicazione:
2022
Citazione:
Phosphine‐Catalyzed [3+2] Cycloaddition of Aza‐Aurones and Allenoates: Enantioselective Synthesis of 2‐Spirocyclopentyl‐Indolin‐3‐Ones / E. Brambilla, C. Pozza, S. Rizzato, G. Abbiati, V. Pirovano. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - (2022 Dec), pp. e202201385.1-e202201385.5. [Epub ahead of print] [10.1002/ejoc.202201385]
Abstract:
An enantioselective phosphine-catalyzed [3+2] cycloaddition between aza-aurones and allenoates is here described. The reaction proceeded under mild reaction conditions to afford 2-spirocyclopentyl indolin-3-one derivatives as single gamma-isomer and with high levels of stereocontrol.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
asymmetric catalysis; cycloaddition; organocatalysis; phosphanes; spiro compounds
Elenco autori:
E. Brambilla, C. Pozza, S. Rizzato, G. Abbiati, V. Pirovano
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