Phosphine‐Catalyzed [3+2] Cycloaddition of Aza‐Aurones and Allenoates: Enantioselective Synthesis of 2‐Spirocyclopentyl‐Indolin‐3‐Ones

Articolo

Data di Pubblicazione:

2022

Citazione:

Phosphine‐Catalyzed [3+2] Cycloaddition of Aza‐Aurones and Allenoates: Enantioselective Synthesis of 2‐Spirocyclopentyl‐Indolin‐3‐Ones / E. Brambilla, C. Pozza, S. Rizzato, G. Abbiati, V. Pirovano. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - (2022 Dec), pp. e202201385.1-e202201385.5. [Epub ahead of print] [10.1002/ejoc.202201385]

Abstract:

An enantioselective phosphine-catalyzed [3+2] cycloaddition between aza-aurones and allenoates is here described. The reaction proceeded under mild reaction conditions to afford 2-spirocyclopentyl indolin-3-one derivatives as single gamma-isomer and with high levels of stereocontrol.

Tipologia IRIS:

01 - Articolo su periodico

Keywords:

asymmetric catalysis; cycloaddition; organocatalysis; phosphanes; spiro compounds

Elenco autori: