Data di Pubblicazione:
2022
Citazione:
Erythrophagocytic multiple myeloma in a dog / P. Romanelli, C. Recordati, P. Rigamonti, W. Bertazzolo. - In: JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION. - ISSN 1040-6387. - 34:4(2022 Jul), pp. 718-722. [10.1177/10406387221092299]
Abstract:
A 5-y-old spayed female Golden Retriever dog was referred because of severe normocytic normochromic nonregenerative anemia and thrombocytopenia. Serum analysis revealed hyperproteinemia and monoclonal or oligoclonal gammopathy. Fine-needle aspiration of the spleen revealed a highly erythrophagocytic population of neoplastic round cells, morphologically suggestive of plasma cells. After euthanasia, histologic assessment of the spleen and liver revealed an erythrophagocytic round cell tumor. Immunohistochemical analysis of the tumor population was positive for MUM1p and negative for CD3, CD20, and Iba-1, confirming the plasma cell origin of the tumor. Erythrophagocytic multiple myeloma is a very rare neoplastic condition in dogs.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
MUM1p; anemia; dogs; erythrophagocytosis; hypoalbuminemia; immunohistochemistry; monoclonal gammopathy; multiple myeloma; plasma cells; thrombocytopenia; Animals; Dogs; Female; Liver; Spleen; Dog Diseases; Multiple Myeloma
Elenco autori:
P. Romanelli, C. Recordati, P. Rigamonti, W. Bertazzolo
Link alla scheda completa: