Safe administration of an inactivated virosomal adjuvanted influenza vaccine in asthmatic children with egg allergy
Articolo
Data di Pubblicazione:
2008
Citazione:
Safe administration of an inactivated virosomal adjuvanted influenza vaccine in asthmatic children with egg allergy / S. Esposito, C. Gasparini, A. Martelli, A. Zenga, E. Tremolati, E. Varin, G.L. Marseglia, A. Fiocchi, N. Principi. - In: VACCINE. - ISSN 0264-410X. - 26:36(2008 Aug 26), pp. 4664-4668.
Abstract:
In order to evaluate whether the virosomal adjuvanted influenza vaccine that has been shown to have the lowest egg protein content (Inflexal V, Berna Biotech) could be administered to children with even severe egg allergy without any risk of allergic reactions, we used epicutaneous skin testing with the undiluted vaccine in 88 asthmatic children (44 with and 44 without egg allergy), none of whom had a positive response. They were then vaccinated with the whole dose of Inflexal V intramuscularly in a one-dose protocol, and the occurrence of any immediate or delayed adverse events were actively monitored for 28 days. The results showed the safety of the administration, and demonstrated that Inflexal V can be safely given without performing a vaccine skin test in children with any kind of egg allergy.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Allergy; Asthma; Children; Egg allergy; Influenza; Influenza vaccination; Vaccine
Elenco autori:
S. Esposito, C. Gasparini, A. Martelli, A. Zenga, E. Tremolati, E. Varin, G.L. Marseglia, A. Fiocchi, N. Principi
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