Highly enantioselective Rh-catalyzed hydrogenations with heterocombinations of pentafluorobenzyl- and methoxybenzyl-derived binaphthyl phosphites
Articolo
Data di Pubblicazione:
2008
Citazione:
Highly enantioselective Rh-catalyzed hydrogenations with heterocombinations of pentafluorobenzyl- and methoxybenzyl-derived binaphthyl phosphites / B. Lynikaite, J. Cvengros, U. Piarulli, C.M.A. Gennari. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 49:5(2008), pp. 755-759.
Abstract:
The Rh-catalyzed hydrogenations of dimethyl itaconate and methyl acetamido acrylate using selected heterocombinations of pentafluorobenzyl- and methoxybenzyl-derived binaphthyl phosphites proved to be highly enantioselective (ee 93–99%). In these selected cases the Rh-heterocomplexes, which were formed in a statistical amount (ca. 50% by 31P NMR), turned out to be more active and selective than the two homocomplexes.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Asymmetric hydrogenation; Enantioselective catalysis; Phosphites; Rhodium
Elenco autori:
B. Lynikaite, J. Cvengros, U. Piarulli, C.M.A. Gennari
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