Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound
Articolo
Data di Pubblicazione:
2022
Citazione:
Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound / N. Graziano, C. Agostoni, F. Chiaraviglio, C. Betti, A. Piffer, M.G. Bianchetti, G.P. Milani. - In: THE ITALIAN JOURNAL OF PEDIATRICS. - ISSN 1720-8424. - 48:1(2022 Jan 24), pp. 14.1-14.4. [10.1186/s13052-022-01203-y]
Abstract:
Background: The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation: Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions: Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Acidosis; Aldosterone; children; infants; Hyponatremia; Infection; Pyelonephritis; Sonography;
Elenco autori:
N. Graziano, C. Agostoni, F. Chiaraviglio, C. Betti, A. Piffer, M.G. Bianchetti, G.P. Milani
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