Data di Pubblicazione:
2006
Citazione:
Vesicular transmitter release from astrocytes / V. Montana, E.B. Malarkey, C. Verderio, M. Matteoli, V. Parpura. - In: GLIA. - ISSN 0894-1491. - 54:7(2006 Nov 15), pp. 700-715.
Abstract:
Astrocytes can release a variety of transmitters, including glutamate and ATP, in response to stimuli that induce increases in intracellular Ca(2+) levels. This release occurs via a regulated, exocytotic pathway. As evidence of this, astrocytes express protein components of the vesicular secretory apparatus, including synaptobrevin 2, syntaxin, and SNAP-23. Additionally, astrocytes possess vesicular organelles, the essential morphological elements required for regulated Ca(2+)-dependent transmitter release. The location of specific exocytotic sites on these cells, however, remains to be unequivocally determined.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
ATP; Ca2+ excitability; Exocytosis; Glutamate; SNARE proteins; Synapse; Vesicle
Elenco autori:
V. Montana, E.B. Malarkey, C. Verderio, M. Matteoli, V. Parpura
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