Re-thinking diabetic nephropathy: Microalbuminuria is just a piece of the diagnostic puzzle
Articolo
Data di Pubblicazione:
2022
Citazione:
Re-thinking diabetic nephropathy: Microalbuminuria is just a piece of the diagnostic puzzle / D. Ceccarelli Ceccarelli, R. Paleari, B. Solerte, A. Mosca. - In: CLINICA CHIMICA ACTA. - ISSN 0009-8981. - 524:(2022 Jan 01), pp. 146-153. [10.1016/j.cca.2021.11.009]
Abstract:
The decline of the estimated glomerular filtration rate (eGFR) and the presence of albuminuria are the typical hallmarks of kidney disease arising as one of the most frequent diabetic complications over a long period of time, generally known as diabetic nephropathy or diabetes kidney disease (DKD). However, a decline in the renal function may occur in diabetic patients for other reasons unrelated to glycemic control, and this condition is known as non-diabetic kidney disease (NDKD). In this opinion paper we will review these conditions, and we outline the importance of other investigations, such as kidney biopsy and the measurement of novel biomarkers, in order to identify the disease progression early, and to allow a timely intervention. We will also focus on the actual limits of the quantitative measurements of albumin in urine, especially with regards to potential interferences due to the treatment of patients with statins.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Albuminuria; Diabetes; Kidney disease; Statins; Albuminuria; Humans; Diabetes Mellitus; Diabetic Nephropathies;
Elenco autori:
D. Ceccarelli Ceccarelli, R. Paleari, B. Solerte, A. Mosca
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