Panton-valentine leukocidin Staphylococcus aureus severe infection in an infant: a case report and a review of the literature
Articolo
Data di Pubblicazione:
2021
Citazione:
Panton-valentine leukocidin Staphylococcus aureus severe infection in an infant: a case report and a review of the literature / M.L. Castellazzi, S. Bosis, I. Borzani, C. Tagliabue, R. Pinzani, P. Marchisio, G.M. di Pietro. - In: THE ITALIAN JOURNAL OF PEDIATRICS. - ISSN 1720-8424. - 47:1(2021), pp. 158.1-158.9. [10.1186/s13052-021-01105-5]
Abstract:
Background: Panton-Valentine leukocidin (PVL) is one of the major virulence factor of Staphylococcus aureus (SA) that might be associated with invasive life-threating infections. A prompt diagnosis and adequate treatment are essential in achieving the best outcome and avoiding serious sequelae. We describe a case of severe invasive PVL-SA infection in an infant. A literature review starting from 2010 was also performed in order to discuss clinical presentations, radiological findings, treatment and outcome. Case presentation: This is a case of a 6-month-old boy who rapidly developed high fever and poor general condition. He was diagnosed as having multiple muscular abscesses, multiple foci of osteomyelitis and bloodstream infections caused by Panton-Valentine leukocidin Methicillin-resistant Staphylococcus aureus. He received intravenous antibiotics and surgical drainage of the abscess with progressive recovery. Conclusion: Our report highlights the importance of improving awareness of this severe infection, as a prompt diagnosis and adequate manage is essential in order to save life and to prevent serious complications.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Panton-valentine leukocidin; Staphylococcus aureus; Children; Infection
Elenco autori:
M.L. Castellazzi, S. Bosis, I. Borzani, C. Tagliabue, R. Pinzani, P. Marchisio, G.M. di Pietro
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