The pneumonia severity index predicts time to clinical stability in patients with community-acquired pneumonia
Articolo
Data di Pubblicazione:
2006
Citazione:
The pneumonia severity index predicts time to clinical stability in patients with community-acquired pneumonia / F. Arnold, A. LaJoie, T. Marrie, P. Rossi, F. Blasi, C. Luna, P. Fernandez, J. Porras, K. Weiss, C. Feldman, E. Rodriguez, G. Levy, F. Arteta, J. Roig, J. Rello, J. Ramirez, Community-Acquired Pneumonia Organization. - In: INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE. - ISSN 1027-3719. - 10:7(2006), pp. 739-743.
Abstract:
SETTING: A total of 33 hospitals in 13 countries in North America, Europe, Africa, Asia and Latin America.
OBJECTIVE: To investigate the relationship between the pneumonia severity index (PSI) and the time to clinical stability from intravenous to oral antibiotic therapy in hospitalized adult patients with community-acquired pneumonia (CAP).
DESIGN: An international, retrospective, observational study of random adult patients meeting the definition of CAP between June 2001 and May 2004.
RESULTS: The risk class (RC) according to the PSI was
calculated for all patients. The criteria to define when a
patient is clinically stable were evaluated daily during
the first 7 days of hospitalization in all patients. The
mean time to clinical stability for 254 patients in RC I
was 4.2 days, for 233 patients in RC II it was 3.9 days,
for 395 patients in RC III it was 4.6 days, for 644 patients
in RC IV it was 5.0 days and for 296 patients in
RC V it was 6.0 days. Significant positive correlations
were observed between RC and time to clinical stability
(P 0.0001).
CONCLUSION: The PSI is a tool that can be used to predict
time to clinical stability (i.e., time to antimicrobial switch therapy) in hospitalized patients with CAP.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Community-acquired infection; Length of stay; Pneumonia
Elenco autori:
F. Arnold, A. LaJoie, T. Marrie, P. Rossi, F. Blasi, C. Luna, P. Fernandez, J. Porras, K. Weiss, C. Feldman, E. Rodriguez, G. Levy, F. Arteta, J. Roig, J. Rello, J. Ramirez, Community-Acquired Pneumonia Organization
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