Persona
D'AMATO ALFONSINA
PROFESSORE ASSOCIATO
Pubblicazioni (85)
Ricerca e didattica presso enti (4)
Responsabile corso di Chimica Analitica, linea MZ, Facoltà di Farmacia presso: Università degli Studi di MILANO
(28/02/2018 - )20180228
Incarico svolto presso: Università degli Studi di MILANO
(01/12/2017 - 01/12/2020)20171201
Proteomics Senior Researcher presso: Institute of Food Research
(01/08/2016 - )20160801
Clinical Proteomics Research Associate presso: University of Manchester
(11/08/2014 - 31/07/2016)20140811
No Results Found
Collegi di dottorato (6)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2023
(ciclo: 39 - Anno: 2023
2023
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2022
(ciclo: 38 - Anno: 2022
2022
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2021
(ciclo: 37 - Anno: 2021
2021
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2020
(ciclo: 36 - Anno: 2020
2020
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2019
(ciclo: 35 - Anno: 2019
2019
)
Università degli Studi di MILANO -
SCIENZE FARMACEUTICHE-2018
(ciclo: 34 - Anno: 2018
2018
)
No Results Found
Description
D'Amato Alfonsina, PhD
alfonsina.damato@unimi.it
Academic Employment
December 2020-until now: Associate Professor Department of Pharmaceutical Sciences, University of Milan, SSD CHIM/01 Analytical Chemistry
Principal duties
1) Lead OMICS research area in bioanalytical chemistry
2) Lead of Analytical and Bioanalytical Chemistry undergraduate Course
3) Supervisors of PhD and master students
December 2017– November 2020: RtdB Analytical Chemistry (Senior Researcher/Assistant Professor) Department of Pharmaceutical Sciences, Università degli Studi di Milano.
Principal duties:
1) Lead proteomics research area in medicinal chemistry
2) Lead of Analytical Chemistry Course, undergraduate course
3) Supervisors of PhD and master students
August 2016 – November 2017: Proteomics Senior Research Scientist (indefinite time contract), Analytical Support Unit, Institute of Food Research, Norwich, UK
Principal duties:
1) Lead the Proteomic Unit; 2) Research collaborations in IFR and external projects; 3) Study of molecular mechanisms and interactions between microbiota, health and diseases.
Graduate and post graduate student supervising and training.
August 2014 - July 2016: Research Associate in Clinical Proteomics, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester
Principal duties:
Lead of Research Projects: 1) Study of early biomarkers in Ovarian Cancer patient sera (UKCTOCS project). 2) Study of Epithelial-Mesenchymal Transition associated phenotype in Ovarian Cancer by Quantitative Proteomics.
Laboratory Training of undergraduate students of Proteomic Course
Supervision of PhD and students
February 2010 – July 2014: Senior Post doc (assegnista di ricerca) at Proteomics of Food Allergy and Safety Laboratory, in Chemistry, Material and Chemical Engineering Department "Giulio Natta" (CMIC), Politecnico di Milano
Principal duties:
Lead of Research Projects: 1) Discovery of new potentially allergens by Proteomic approach; 2) Proteome fingerprinting of food; 3) Study of Urokinase and its implication in use in cardiac disease.
Design, implementation and management of mass spectrometry and bioinformatics laboratory to develop Proteomic of Food applications.
February 2005 – December 2009: Post doc (Co.Co.Pro. contract) at Biological Mass Spectrometry Unit, Fondazione Ospedale San Raffaele, Milano.
Principal duties:
Researcher Assistant in Lung Cancer Project, to study sera patient treated or not by EGFR-TKIS, in collaboration with Oncology Division.
Lead of the study: Proteomics Analysis of Nucleolar SUMO-1 Target Proteins upon Proteasome Inhibition.
Lead of the study on allergens in cow’s whey and latex in collaboration with CMIC, Politecnico di Milano and UMR CNRS Paris.
RESEARCH INTEREST
Analytical methods in protein and small molecules studies. Quantitative mass spectrometry-based proteomics in Culture Heritage, Medicinal Chemistry. Cancer. Cardiovascular and metabolic Diseases.
Education
2019-2028 “Abilitazione scientifica nazionale” as Associate Professor in Analytical Chemistry, 03A1 (CHIM01) (art.16, comma1, Legge 240/10)
2014-2023 “Abilitazione scientifica nazionale” as Associate Professor in Biochemistry 05/E1 (BIO 10)
April 2005: PhD in chemistry Università degli Studi di Salerno. The tesi presented and discussed was entitled: Identification of proteins involved in molecular events by using mass spectrometry-based proteomics
October 2001: Laurea in chemistry, Università degli Studi di Salerno. The tesi presented and discussed was entitled: Proteomics identification of acyl-acceptor and acyl-donor substrates for transglutaminase in a human intestinal epithelial cell line. Implications for celiac disease.
Foreign Experiences:
1) January 2000- July 2000 Erasmus Fellowship during Chemistry degree of 6 months at Chemistry Department of University of Leeds.
2) September 2013 - September 2014: 1 year of PhD, by a Marie Curie Fellowship, in Proteomic Laboratory of Astbury Centre, University of Leeds
3) August 2014-July 2016: Research Associate in Clinical Proteomics, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester
4) August 2016- until November 2017: Leader of Proteomics Support Unit (indefinite contract as Senior Research Scientist), Analytical Support Unit, Institute of Food Research, Norwich, UK
Bibliometrics on scopus, updated November 2021:
Scopus Author ID:7007065191
Orcid ID:00000002 8147 7235
Printed papers: 68
Total citations: 1406
H-index:23
Awards. •
•ERASMUS fellowship (6 months), University of Leeds
•MARIE CURIE PhD fellowship (12 months), Astbury Centre, University of Leeds
•First prize winner as best poster Itpa 4th Annual Nation Conference Milano Italy
•EMBO Fellowship to attend Pratical course “Ubiquitin and SUMO”
Selected peer reviewed papers
1) D'Amato A, Di Cesare Mannelli L, Lucarini E, Man AL, Le Gall G, Branca JJV, Ghelardini C, Amedei A, Bertelli E, Regoli M, Pacini A, Luciani G, Gallina P, Altera A, Narbad A, Gulisano M, Hoyles L, Vauzour D, Nicoletti C. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients. Microbiome. 2020; 8(1):140.
2) Nukala SB, Regazzoni L, Aldini G, Zodda E, Tura-Ceide O, Mills NL, Cascante M, Carini M, D'Amato A. Differentially Expressed Proteins in Primary Endothelial Cells Derived From Patients With Acute Myocardial Infarction. Hypertension. 2019;74: 947-956.
3) Nukala SB, Baron G, Aldini G, Carini M, D'Amato A. Mass Spectrometry-based Label-free Quantitative Proteomics To Study the Effect of 3PO Drug at Cellular Level. ACS Med Chem Lett. 2019; 10: 577-583.
4) Cardona EEG, Heathcote K, Teran LM, Righetti PG, Boschetti E, D'Amato A. Novel low-abundance allergens from mango via combinatorial peptide libraries treatment:A proteomics study. Food Chem. 2018, 269:652-660.
5) D'Amato A, Zilberstein G, Zilberstein S, Compagnoni BL, Righetti PG. Of mice and men: Traces of life in the death registries of the 1630 plague in Milano. J Proteomics. 2018: S1874-3919.
alfonsina.damato@unimi.it
Academic Employment
December 2020-until now: Associate Professor Department of Pharmaceutical Sciences, University of Milan, SSD CHIM/01 Analytical Chemistry
Principal duties
1) Lead OMICS research area in bioanalytical chemistry
2) Lead of Analytical and Bioanalytical Chemistry undergraduate Course
3) Supervisors of PhD and master students
December 2017– November 2020: RtdB Analytical Chemistry (Senior Researcher/Assistant Professor) Department of Pharmaceutical Sciences, Università degli Studi di Milano.
Principal duties:
1) Lead proteomics research area in medicinal chemistry
2) Lead of Analytical Chemistry Course, undergraduate course
3) Supervisors of PhD and master students
August 2016 – November 2017: Proteomics Senior Research Scientist (indefinite time contract), Analytical Support Unit, Institute of Food Research, Norwich, UK
Principal duties:
1) Lead the Proteomic Unit; 2) Research collaborations in IFR and external projects; 3) Study of molecular mechanisms and interactions between microbiota, health and diseases.
Graduate and post graduate student supervising and training.
August 2014 - July 2016: Research Associate in Clinical Proteomics, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester
Principal duties:
Lead of Research Projects: 1) Study of early biomarkers in Ovarian Cancer patient sera (UKCTOCS project). 2) Study of Epithelial-Mesenchymal Transition associated phenotype in Ovarian Cancer by Quantitative Proteomics.
Laboratory Training of undergraduate students of Proteomic Course
Supervision of PhD and students
February 2010 – July 2014: Senior Post doc (assegnista di ricerca) at Proteomics of Food Allergy and Safety Laboratory, in Chemistry, Material and Chemical Engineering Department "Giulio Natta" (CMIC), Politecnico di Milano
Principal duties:
Lead of Research Projects: 1) Discovery of new potentially allergens by Proteomic approach; 2) Proteome fingerprinting of food; 3) Study of Urokinase and its implication in use in cardiac disease.
Design, implementation and management of mass spectrometry and bioinformatics laboratory to develop Proteomic of Food applications.
February 2005 – December 2009: Post doc (Co.Co.Pro. contract) at Biological Mass Spectrometry Unit, Fondazione Ospedale San Raffaele, Milano.
Principal duties:
Researcher Assistant in Lung Cancer Project, to study sera patient treated or not by EGFR-TKIS, in collaboration with Oncology Division.
Lead of the study: Proteomics Analysis of Nucleolar SUMO-1 Target Proteins upon Proteasome Inhibition.
Lead of the study on allergens in cow’s whey and latex in collaboration with CMIC, Politecnico di Milano and UMR CNRS Paris.
RESEARCH INTEREST
Analytical methods in protein and small molecules studies. Quantitative mass spectrometry-based proteomics in Culture Heritage, Medicinal Chemistry. Cancer. Cardiovascular and metabolic Diseases.
Education
2019-2028 “Abilitazione scientifica nazionale” as Associate Professor in Analytical Chemistry, 03A1 (CHIM01) (art.16, comma1, Legge 240/10)
2014-2023 “Abilitazione scientifica nazionale” as Associate Professor in Biochemistry 05/E1 (BIO 10)
April 2005: PhD in chemistry Università degli Studi di Salerno. The tesi presented and discussed was entitled: Identification of proteins involved in molecular events by using mass spectrometry-based proteomics
October 2001: Laurea in chemistry, Università degli Studi di Salerno. The tesi presented and discussed was entitled: Proteomics identification of acyl-acceptor and acyl-donor substrates for transglutaminase in a human intestinal epithelial cell line. Implications for celiac disease.
Foreign Experiences:
1) January 2000- July 2000 Erasmus Fellowship during Chemistry degree of 6 months at Chemistry Department of University of Leeds.
2) September 2013 - September 2014: 1 year of PhD, by a Marie Curie Fellowship, in Proteomic Laboratory of Astbury Centre, University of Leeds
3) August 2014-July 2016: Research Associate in Clinical Proteomics, Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester
4) August 2016- until November 2017: Leader of Proteomics Support Unit (indefinite contract as Senior Research Scientist), Analytical Support Unit, Institute of Food Research, Norwich, UK
Bibliometrics on scopus, updated November 2021:
Scopus Author ID:7007065191
Orcid ID:00000002 8147 7235
Printed papers: 68
Total citations: 1406
H-index:23
Awards. •
•ERASMUS fellowship (6 months), University of Leeds
•MARIE CURIE PhD fellowship (12 months), Astbury Centre, University of Leeds
•First prize winner as best poster Itpa 4th Annual Nation Conference Milano Italy
•EMBO Fellowship to attend Pratical course “Ubiquitin and SUMO”
Selected peer reviewed papers
1) D'Amato A, Di Cesare Mannelli L, Lucarini E, Man AL, Le Gall G, Branca JJV, Ghelardini C, Amedei A, Bertelli E, Regoli M, Pacini A, Luciani G, Gallina P, Altera A, Narbad A, Gulisano M, Hoyles L, Vauzour D, Nicoletti C. Faecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients. Microbiome. 2020; 8(1):140.
2) Nukala SB, Regazzoni L, Aldini G, Zodda E, Tura-Ceide O, Mills NL, Cascante M, Carini M, D'Amato A. Differentially Expressed Proteins in Primary Endothelial Cells Derived From Patients With Acute Myocardial Infarction. Hypertension. 2019;74: 947-956.
3) Nukala SB, Baron G, Aldini G, Carini M, D'Amato A. Mass Spectrometry-based Label-free Quantitative Proteomics To Study the Effect of 3PO Drug at Cellular Level. ACS Med Chem Lett. 2019; 10: 577-583.
4) Cardona EEG, Heathcote K, Teran LM, Righetti PG, Boschetti E, D'Amato A. Novel low-abundance allergens from mango via combinatorial peptide libraries treatment:A proteomics study. Food Chem. 2018, 269:652-660.
5) D'Amato A, Zilberstein G, Zilberstein S, Compagnoni BL, Righetti PG. Of mice and men: Traces of life in the death registries of the 1630 plague in Milano. J Proteomics. 2018: S1874-3919.