Acute effects of positive end-expiratory pressure on left ventricle diastolic function in healthy subjects
Articolo
Data di Pubblicazione:
2009
Citazione:
Acute effects of positive end-expiratory pressure on left ventricle diastolic function in healthy subjects / A. Maestroni, S. Aliberti, O. Amir, G. Milani, A.M. Brambilla, F. Piffer, F. Tardini, R. Cosentini. - In: INTERNAL AND EMERGENCY MEDICINE. - ISSN 1828-0447. - 4:3(2009), pp. 249-254.
Abstract:
We evaluated the acute effect of the application of positive end-expiratory pressure (PEEP) on LV diastolic function in 10 healthy subjects. We assessed load dependent diastolic function by Doppler examination of transmitral flow and load independent diastolic function by color M-mode propagation velocity of early flow into the LV cavity (Vp). During the application of PEEP in comparison to the baseline, we found a significant reduction of the E wave peak velocity [79 (64-83) vs. 65 (57-72) cm/s; p = 0.028] and a significant reduction in Vp [84 (73-97) vs. 53 (48-66); p = 0.012]. Moreover, we found a significant reduction in left atrial area [15 (13-18) vs. 12 (10-14) cm2; p = 0.018] and right atrial area [12 (11-15) vs. 11 (9-12) cm2; p = 0.015]. No difference was found in global LV systolic function. The application of PEEP acutely modifies the diastolic flow pattern across the mitral valve, and reduces atrial dimensions.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Cardiopulmonary interactions; Cardiovascular imaging; Non-invasive mechanical ventilation; Positive end-expiratory pressure
Elenco autori:
A. Maestroni, S. Aliberti, O. Amir, G. Milani, A.M. Brambilla, F. Piffer, F. Tardini, R. Cosentini
Link alla scheda completa: