Data di Pubblicazione:
2009
Citazione:
Primary splenic peripheral nerve sheath tumour in a dog / W. Bergmann, I.A. Burgener, P. Roccabianca, U. Rytz, M. Welle. - In: JOURNAL OF COMPARATIVE PATHOLOGY. - ISSN 0021-9975. - 141:2-3(2009 Aug), pp. 195-198. [10.1016/j.jcpa.2009.03.009]
Abstract:
An 8-year-old crossbred dog was presented with a one-month history of progressive weakness, respiratory impairment and abdominal distension. Surgical exploration revealed the presence of a splenic mass that infiltrated the mesentery and was adherent to the stomach and pancreas. The mass was composed of highly cellular areas of spindle-shaped cells arranged in interlacing bundles, streams, whorls and storiform patterns (Antoni A pattern) and less cellular areas with more loosely arranged spindle to oval cells (Antoni B pattern). The majority of neoplastic cells expressed vimentin, S-100 and glial fibrillary acidic protein (GFAP), but did not express desmin, α-smooth muscle actin or factor VIII. These morphological and immunohistochemical findings characterized the lesion as a malignant peripheral nerve sheath tumour (PNST). Primary splenic PNST has not been documented previously in the dog.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
W. Bergmann, I.A. Burgener, P. Roccabianca, U. Rytz, M. Welle
Link alla scheda completa:
Link al Full Text: