Data di Pubblicazione:
2009
Citazione:
New SMAC mimetic compounds as apoptosis inducers / C. Scolastico, L.P. Manzoni, P. Seneci, L. Belvisi, D. Delia, M. Bolognesi, E. Mastrangelo, M. De Mayo De Mari Milani, I.M. Motto, C. Drago.
Abstract:
The present invention relates to compounds conformationally constrained mimetics of Smac with function as inhibitors of Inhibitor of Apoptosis Proteins (IAPs), the invention also relates to the use of these compounds in therapy, wherein the induction of apoptotic cell death is beneficial, especially in the treatment of cancer, alone or in combination with other active ingredients.
Tipologia IRIS:
09 - Brevetto, privativa o norma
Elenco autori:
C. Scolastico, L.P. Manzoni, P. Seneci, L. Belvisi, D. Delia, M. Bolognesi, E. Mastrangelo, M. De Mayo De Mari Milani, I.M. Motto, C. Drago
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