Modeling the role of arterial windkessel in the enhancement and synchronization of low frequency vasomotor activity
Articolo
Data di Pubblicazione:
2003
Citazione:
Modeling the role of arterial windkessel in the enhancement and synchronization of low frequency vasomotor activity / G. Baselli, A. Porta, M. Pagani. - In: COMPUTERS IN CARDIOLOGY. - ISSN 0276-6574. - 30(2003), pp. 41-44.
Abstract:
Arterial windkessel mechanisms and arterial pressure (AP) low frequency (LF) waves were investigated by means of simple lumped models of a compliant resistant/arterial tree and of flow regulation in peripheral vascular districts (PVDs) with three types of feedback: J) delay, 2) Van der Pol oscillator, 3) relay; all were able to actively compensate flow changes and to simulate peripheral LF vasomotion. Each PVD connected to a Windkessel compartment displayed a reduction and a disappearance of oscillations with low compliance, when the Windkessel equivalent time constant T/sub eq/ fall below 2s. Two PVDs connected to the same Windkessel tended to phase opposition with a negative interference canceling their LF oscillations from AP. With a modest neural drive, cancellation was imperfect and AP waves appeared. Vasomotion, arterial compliances and neural triggers are all essential informing LF AP variability.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
G. Baselli, A. Porta, M. Pagani
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