Data di Pubblicazione:
2000
Citazione:
Ecotoxicological soil evaluation by FETAX / M. Prati, E. Biganzoli, P. Boracchi, M. Tesauro, C. Monetti, G. Bernardini. - In: CHEMOSPHERE. - ISSN 0045-6535. - 41:10(2000 Nov), pp. 1621-1628.
Abstract:
The frog embryo teratogenesis assay-Xenopus (FETAX) is a powerful and flexible bioassay that makes use of the embryos of the anuran Xenopus laevis. FETAX satisfies the requirements of low cost, reliability and reproducibility and, thanks to its three endpoints (i.e., mortality, teratogenicity and growth inhibition) can detect the xenobiotics that affect embryonic development. In this paper, we have used FETAX to evaluate samples of soils collected in an oil-contaminated area. Embryos were exposed directly to the soil to be tested. Particular attention was devoted to provide a statistical procedure for analysing mortality and malformation data as well as growth retardation.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Embryo teratogenesis assay; toxicity hazard assessment; 3 carrier solvents; developmental toxicity; xenopus fetax; retinoic acid; validation; mixture; malformation; metabolites
Elenco autori:
M. Prati, E. Biganzoli, P. Boracchi, M. Tesauro, C. Monetti, G. Bernardini
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