alfa,gamma-diamino acids : asymmetric synthesis of new constrained 6-amino-3-azabicyclo[3.2.1]octane-6-carboxylic acids
Articolo
Data di Pubblicazione:
2006
Citazione:
alfa,gamma-diamino acids : asymmetric synthesis of new constrained 6-amino-3-azabicyclo[3.2.1]octane-6-carboxylic acids / F. Caputo, C. Cattaneo, F. Clerici, M.L. Gelmi, S. Pellegrino. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - 71:22(2006), pp. 8467-8472.
Abstract:
The synthesis of two new diastereomeric 6-amino-3-azabicyclo[3.2.1]octane-6-carboxylic acids exo- and
endo-8,9 is reported using exo- and endo-norbornene amino acids as chiral building blocks. This method
provides a fast access to optically pure amino acids 8 and 9 which can be considered both R,Á- and
R,‰-diamino acids containing sterical constraints and characterized by R,R-disubstitution
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
6-amino-3-azabicyclo[3.2.1]octane ; 6-carboxylic acids ; reductive amination
stereochemistry ; alfa-gamma-amino acid
Elenco autori:
F. Caputo, C. Cattaneo, F. Clerici, M.L. Gelmi, S. Pellegrino
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