Molecular and immunohistochemical markers with prognostic and predictive significance in liver metastases from colorectal carcinoma
Articolo
Data di Pubblicazione:
2018
Citazione:
Molecular and immunohistochemical markers with prognostic and predictive significance in liver metastases from colorectal carcinoma / G. Lopez, F. Boggio, S. Ferrero, N. Fusco, A. Del Gobbo. - In: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. - ISSN 1422-0067. - 19:10(2018 Oct), pp. 3014.1-3014.18. [10.3390/ijms19103014]
Abstract:
Despite the significant recent achievements in the diagnosis and treatment of colorectal cancer (CRC), the prognosis of these patients has currently plateaued. During the past few years, the opportunity to consider multiple treatment modalities (including surgery and other locoregional treatments, systemic therapy, and targeted therapy) led to the research of novel prognostic and predictive biomarkers in CRC liver metastases (CRCLM) patients. In this review, we seek to describe the current state of knowledge of CRCLM biomarkers and to outline impending clinical perspectives, in particular focusing on the cutting-edge tools available for their characterization.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Biomarkers; Colorectal cancer; Immunohistochemistry; Liver metastases; Molecular markers; Predictive; Prognostic; Catalysis; Molecular Biology; Spectroscopy; Computer Science Applications1707 Computer Vision and Pattern Recognition; Physical and Theoretical Chemistry; Organic Chemistry; Inorganic Chemistry
Elenco autori:
G. Lopez, F. Boggio, S. Ferrero, N. Fusco, A. Del Gobbo
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