Standard and viscoelastic mechanical properties of respiratory system compartments in dogs : effect of volume, posture, and shape
Articolo
Data di Pubblicazione:
2019
Citazione:
Standard and viscoelastic mechanical properties of respiratory system compartments in dogs : effect of volume, posture, and shape / E. D'Angelo, E. Calderini, M. Tavola, M. Pecchiari. - In: RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY. - ISSN 1569-9048. - 261(2019 Mar), pp. 31-39. [10.1016/j.resp.2018.12.003]
Abstract:
In 9 anesthetized, paralyzed dogs lung and chest-wall standard (viscous resistance, Rint, and quasi-static elastance, Est) and viscoelastic parameters (resistance, Rvel, and time constant, τvel) were measured in the supine posture before and after rib-cage block, after application of an expiratory threshold load, and after 75° head-up tilting before and after wide chest opening. Lung and chest-wall τvel were the same under all conditions. Rvel was independent of volume and posture, and greater for the lung. Chest-wall Rint was independent of flow, volume, and posture. Lung Rint decreased with increasing volume. Chest-wall Rint, Est and Rvel increased with rib-cage block, allowing the assessment of both abdominal-wall and rib-cage characteristics. When chest opening did not elicit bronchoconstriction, the decrease of Rvel was ~6%. Main conclusions: lung and chest-wall exhibit linear tissue viscoelasticity within the range studied; rib-cage and abdomen characteristics are similar, and asynchronous motion is not expected at physiological respiratory rates; in normal lungs, heterogeneity of parallel time constants plays a marginal role.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Abdominal wall; airway resistance; chest wall; lung; mechanics; rib cage; viscoelasticity
Elenco autori:
E. D'Angelo, E. Calderini, M. Tavola, M. Pecchiari
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