Chiral diamine-copper(I) complexes as asymmetric catalysts in the enantioselective addition of phenylacetylene to imines
Articolo
Data di Pubblicazione:
2005
Citazione:
Chiral diamine-copper(I) complexes as asymmetric catalysts in the enantioselective addition of phenylacetylene to imines / S. Orlandi, F. Colombo, M. Benaglia. - In: SYNTHESIS. - ISSN 0039-7881. - 2005:10(2005), pp. 1689-1692.
Abstract:
The stereoselective addition of phenyl acetylene to imines, catalysed by chiral bis-amine-Cu(I) complexes was studied. The chiral ligands are either commercially available or easily prepared in one or two steps. This very convenient and extremely simple experimental procedure at room temperature allowed optically active propargyl amines to be obtained in good yields with enantio-selectivities up to 70%.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
chiral bis-amines; copper complexes; propargylamines; enantioselective catalysis; acetylene addition
Elenco autori:
S. Orlandi, F. Colombo, M. Benaglia
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