Biological, neuroimaging, and neurophysiological markers in frontotemporal dementia : three faces of the same coin
Articolo
Data di Pubblicazione:
2018
Citazione:
Biological, neuroimaging, and neurophysiological markers in frontotemporal dementia : three faces of the same coin / B. Borroni, A. Benussi, E. Premi, A. Alberici, E. Marcello, F. Gardoni, M. Diluca, A. Padovani. - In: JOURNAL OF ALZHEIMER'S DISEASE. - ISSN 1387-2877. - 62:3(2018), pp. 1113-1123. [10.3233/JAD-170584]
Abstract:
Frontotemporal dementia (FTD) is a heterogeneous clinical, genetic, and neuropathological disorder. Clinical diagnosis and prediction of neuropathological substrates are hampered by heterogeneous pictures. Diagnostic markers are key in clinical trials to differentiate FTD from other neurodegenerative dementias. In the same view, identifying the neuropathological hallmarks of the disease is key in light of future disease-modifying treatments. The aim of the present review is to unravel the progress in biomarker discovery, discussing the potential applications of available biological, imaging, and neurophysiological markers.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
biomarkers; cerebrospinal fluid; frontotemporal lobar degeneration; neuroimaging; transcranial magneticstimulation
Elenco autori:
B. Borroni, A. Benussi, E. Premi, A. Alberici, E. Marcello, F. Gardoni, M. Diluca, A. Padovani
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