Data di Pubblicazione:
1991
Citazione:
Primary cutaneous pleomorphic T-cell lymphoma expressing CD30 antigen / R. Gianotti, E. Alessi, S. Cavicchini, E. Berti. - In: AMERICAN JOURNAL OF DERMATOPATHOLOGY. - ISSN 0193-1091. - 13:5(1991 Oct), pp. 503-508.
Abstract:
Pleomorphic peripheral T-cell lymphomas (PPTL) arising primarily in the skin are uncommon. The observation of pleomorphic T-cell lymphoma composed of 100% CD30+ cells is rare. We report the case of a woman in whom such a tumor manifested itself with a single cutaneous lesion. It was composed of medium to large cells expressing markers of helper/inducer T-lymphocytes, as well as activation (CD30) and proliferation antigens (Ki-67), but not the CD25 activation antigen. The lesion was excised and the patient is alive and disease free 2 years after the diagnosis. This case confirms previous reports about the favorable course of some cutaneous pleomorphic lymphomas, and shows that the activation antigen expression and proliferation antigen (Ki-67) expression do not seem to worsen the prognosis.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
antigens, CD; antigens, CD30; antigens, neoplasm; female; gene rearrangement, beta-chain T-cell antigen receptor; gene rearrangement, gamma-chain T-cell antigen receptor; humans; Ki-67 antigen; lymphoma, non-hodgkin; lymphoma, T-cell, cutaneous; middle aged; nuclear proteins; skin neoplasms
Elenco autori:
R. Gianotti, E. Alessi, S. Cavicchini, E. Berti
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