Osseointegration of Titanium Implants with Different Rough Surfaces : a Histologic and Histomorphometric Study in an Adult Minipig Model
Articolo
Data di Pubblicazione:
2017
Citazione:
Osseointegration of Titanium Implants with Different Rough Surfaces : a Histologic and Histomorphometric Study in an Adult Minipig Model / M. Del Fabbro, S. Taschieri, E. Canciani, A. Addis, F. Musto, R. Weinstein, C. Dellavia, M. Del Fabbro. - In: IMPLANT DENTISTRY. - ISSN 1056-6163. - 26:3(2017), pp. 357-366. [10.1097/ID.0000000000000560]
Abstract:
Background: Many chemical and physical modifications of titanium surfaces were introduced, aiming at improving surface bioactivity, but few comparative evidence exists. Objective: To evaluate histologically in minipigs the osseointegration of implants made of commercially pure (CP) titanium or titanium alloy, treated by different roughening procedures. Material and Methods: Three sandblasted acid-etched (SA) surfaces, 2 anodized (AN), and 1 double acid-etched (DAE) were compared. Surface microtopography was characterized with scanning electron microscope; surface element composition was also assessed. One implant per group was inserted in each proximal tibia of 2 minipigs. Three months after healing, block biopsies were taken for histomorphometric analysis. Implant stability quotient (ISQ) was measured at insertion and before harvesting. Results: The highest amount of cortical bone-implant contact was observed around SA implants and showed positive correlation with surface roughness. The greatest increase in ISQ was observed in CP-AN implants. In the medullary region, SA implants showed the best osteogenic response, whereas inflammatory cells were found around DAE and alloy-AN implants. Conclusions: SA surfaces were more osteogenic than anodized or dual acid-etched ones, although not significantly. Surface roughness affected osseointegration.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
bone healing; dental implants; implant surface; animal model; oral Surgery
Elenco autori:
M. Del Fabbro, S. Taschieri, E. Canciani, A. Addis, F. Musto, R. Weinstein, C. Dellavia, M. Del Fabbro
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