Data di Pubblicazione:
2017
Citazione:
Silver Catalyzed Domino Approach to 1,3-Dicarbosubstituted Isochromenes / M. Dell'Acqua, V. Pirovano, S. Peroni, G. Tseberlidis, D. Nava, E. Rossi, G. Abbiati. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2017:11(2017 Mar 21), pp. 1425-1433. [10.1002/ejoc.201601602]
Abstract:
We report herein the first example of the silver triflate catalysed synthesis of 1,3-dicarbo-substituted isochromene derivatives starting from 2-alkynyl(hetero)arylaldehydes and enolizable ketones. The reaction proceeds in a cascade fashion under mild heating with complete regioselectivity and moderate-to-good yields. In some cases, the reaction gives unexpected homodimeric products. Two competitive mechanistic paths for the formation of the desired isochromene derivatives and the homodimeric products are described.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
isochromenes; alkynes; isochromenylium; domino reaction; silver
Elenco autori:
M. Dell'Acqua, V. Pirovano, S. Peroni, G. Tseberlidis, D. Nava, E. Rossi, G. Abbiati
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