Data di Pubblicazione:
2005
Citazione:
Modulation of macrophage function and metabolism / S. Bellosta, F. Bernini (HANDBOOK OF EXPERIMENTAL PHARMACOLOGY). - In: Atherosclerosis : diet and drugs / [a cura di] A. von Eckardstein. - Berlin : Springer, 2005. - ISBN 9783540225690. - pp. 665-695 [10.1007/3-540-27661-0_25]
Abstract:
Several drugs or pharmacologically active molecules such as statins, calcium antagonists, and PPAR agonists have been shown to affect macrophage functions that contribute to atherosclerosis and modulate plaque stability. For example, the modulation of matrix metalloproteinase secretion and cholesterol metabolism in macrophages may help to prevent cardiovascular disease independently of the correction of risk factors.
Tipologia IRIS:
03 - Contributo in volume
Keywords:
Atherosclerosis; cholesterol metabolism; drug treatment; inflammation; matrix metalloproteinase; pleiotropic effects
Elenco autori:
S. Bellosta, F. Bernini
Link alla scheda completa:
Titolo del libro:
Atherosclerosis : diet and drugs