Data di Pubblicazione:
2017
Citazione:
Serum antibodies to glycans in peripheral neuropathies / S. Sonnino, E. Chiricozzi, M.G. Ciampa, L. Mauri, A. Prinetti, G. Toffano, M. Aureli. - In: MOLECULAR NEUROBIOLOGY. - ISSN 0893-7648. - 54:2(2017 Mar), pp. 1564-1567. [10.1007/s12035-016-9775-8]
Abstract:
In peripheral neuropathies, such as sensorimotor neuropathies, motor neuron diseases, or the Guillain-Barré syndrome,
serum antibodies recognizing saccharide units, portion of oligosaccharides, or oligosaccharide chains, have been found. These antibodies are called anti-glycosphingolipid (GSL) or anti-ganglioside antibodies.However, the information on the aglycone carrying the hydrophilic oligosaccharide remains elusive. The absolute and unique association of GSL to the onset, development and symptomatology of the peripheral neuropathies could be misleading. Here, we report some thoughts on the matter.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
peripheral neuropathies; serumantibodies; oligosaccharides; glycoconjugates; mimicry
Elenco autori:
S. Sonnino, E. Chiricozzi, M.G. Ciampa, L. Mauri, A. Prinetti, G. Toffano, M. Aureli
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