Cyclopamine-paclitaxel-containing nanoparticles : internalization in cells detected by confocal and super-resolution microscopy
Articolo
Data di Pubblicazione:
2015
Citazione:
Cyclopamine-paclitaxel-containing nanoparticles : internalization in cells detected by confocal and super-resolution microscopy / G. Fumagalli, D. Mazza, M.S. Christodoulou, G. Damia, F. Ricci, D. Perdicchia, B. Stella, F. Dosio, P.A. Sotiropoulou, D. Passarella. - In: CHEMPLUSCHEM. - ISSN 2192-6506. - 80:9(2015), pp. 1380-1383. [10.1002/cplu.201500156]
Abstract:
Cyclopamine- and paclitaxel-containing hetero-nanoparticles generated by self-assembly show combined efficacy in the treatment of three different cancer cell lines. The use of ternary combination with the addition of a dye-squalene conjugate secured the obtainment of fluorescent nanoparticles that permitted the observation of the cellular internalization by confocal microscopy and super-resolution dSTORM (direct stochastic optical reconstruction microscopy).
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
cancer stem cells; cyclopamine; nanoparticles; paclitaxel; chemistry (all)
Elenco autori:
G. Fumagalli, D. Mazza, M.S. Christodoulou, G. Damia, F. Ricci, D. Perdicchia, B. Stella, F. Dosio, P.A. Sotiropoulou, D. Passarella
Link alla scheda completa: