Data di Pubblicazione:
2012
Citazione:
The JNK signalling transduction pathway in the brain / X. Antoniou, T. Borsello. - In: FRONTIERS IN BIOSCIENCE. - ISSN 1945-0494. - 4E:6(2012), pp. 2110-2120. [10.2741/528]
Abstract:
Among the numerous intracellular signalling pathways that control brain development and pathogenesis c-Jun N-terminal kinases have a leading role in the Central Nervous System. JNKs regulate a wide range of processes in brain development, plasticity, repair/regeneration, neuronal death and neuroinflammation. Indeed, accumulating evidence underline the potential of JNK targeted molecules towards the treatment of neurodegenerative disorders. The focus of the presenting review is to provide an overview of the reported data linking JNKs to brain function and dysfunction.
Tipologia IRIS:
01 - Articolo su periodico
Elenco autori:
X. Antoniou, T. Borsello
Link alla scheda completa: