Well-defined [Ag(I)(Pc-L)] complexes: suitable catalysts for the synthesis of 1-Alkoxy-isocromenes
Abstract
Data di Pubblicazione:
2014
Citazione:
Well-defined [Ag(I)(Pc-L)] complexes: suitable catalysts for the synthesis of 1-Alkoxy-isocromenes / M. Dell’Acqua, B. Castano, T. Pedrazzini, V. Pirovano, E. Rossi, A. Caselli, G. Abbiati - In: Co.Gi.Co 2014 / [a cura di] E. Licandro, F. Ragaini. - Prima edizione. - Milano : EdiSES, 2014 Jun. - ISBN 9788879598224. - pp. 59-59 (( Intervento presentato al 11. convegno Congresso del Gruppo interdivisionale di chimica organometallica tenutosi a Milano nel 2014.
Abstract:
The [Ag(I)(Pc-L)] complexes – new silver(I) complex with an original macrocyclic pyridine-containing ligand (Pc-L) – demonstrated to be suitable catalysts for the synthesis of 1-alkoxyisocromenes starting from various 2-alkynylbenzaldehydes and different primary and secondary alcohols. Best results were obtained with BF4- complex. The approach is characterised by absolute regioselectivity, mild reaction condition, good to excellent reaction yields, cleanness of the reaction and reduced purification steps. The reaction mechanism was investigated by in depth NMR studies and an aimed intramolecular “trapping” experiment to point out the possible involvement of an isochromenilium intermediate. In an enantioselective development perspective, some preliminary tests with Ag(I) complexes of previously synthesised chiral pyridine-containing ligands1b were performed.
Tipologia IRIS:
03 - Contributo in volume
Keywords:
domino reactions; homogeneous catalysis; silver; macrocycles; oxygen heterocycles
Elenco autori:
M. Dell’Acqua, B. Castano, T. Pedrazzini, V. Pirovano, E. Rossi, A. Caselli, G. Abbiati
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Titolo del libro:
Co.Gi.Co 2014