Data di Pubblicazione:
2008
Citazione:
Valvole cardiache ingegnerizzate : stato dell’arte / L. Dainese, F. Barili, D. Andreini, A. Guarino, B. Micheli, C.A. Borsetti, G. Polvani, A. Parolari, M. Fusari, P. Biglioli. - In: GIORNALE ITALIANO DI CARDIOLOGIA. - ISSN 1827-6806. - 9:3(2008 Mar), pp. 167-172.
Abstract:
Engineered heart valves promise to be the ideal heart valve replacement: they have the potential to grow and repair within the host, to minimize inflammatory and immunological responses and to limit thromboembolism. In particular, pediatric patients with congenital defects would greatly benefit from growing replacement materials by reducing the need for surgical reinterventions due to the lack of prosthetic material growth. In fact, viable cells included in engineered heart valves can theoretically adapt to a growing and changing environment exactly as a native biological structure. Engineered heart valves represent thus a novel experimental approach to create autologous, living replacements with the potential to grow, regenerate, and remodel. The aim of this paper is to present a review concerning the research efforts to create a viable engineered heart valve.
Tipologia IRIS:
01 - Articolo su periodico
Keywords:
Decellularized scaffold; Heart valves; Tissue engineering; Valvular scaffold
Elenco autori:
L. Dainese, F. Barili, D. Andreini, A. Guarino, B. Micheli, C.A. Borsetti, G. Polvani, A. Parolari, M. Fusari, P. Biglioli
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